Dr. J. Karuna,

Therapeutic Trial with Myron in Leucorrhoea

Dr. J. Karuna, MD, DGO, Professor of Obstetrics & Gynaecology

Rangaraya Medical College and Obstetrician & Gynaecologist Govt. General Hospital, Kakinada (A.P.)

Leucorrhoea is the most common complaint in women. It occurs in one out of every third of all the Gynaecological cases. It is caused by various infections both specific and non­specific.

Myron has been described to be beneficial in the treatment of Leucorrhoea. It is described to have anti-inflammatory, antibacterial, antisep­tic and haematinic properties and is claimed to increase uterine tone.

The present study has been undertaken with a view to record our clinical experience in the use of Ayurvedic compound “MYRON”. Non­specific and specific leucorrhoea in non-pre­gnant women was treated with the drug.

Pharmacotherapeutic of Drug:

Each tablet of Myron contains:

Hirabol 75.0 mg., Guggul 30.0 mg., Bang Bhasma 15.0 mg., Kasis Bhasma 15.0 mg., Shilajit 15.0 mg., Lodhar 15.0 mg., Dhavdi Flower 15.0 mg., Ardusi Leaves 7.5 mg., Ardusi Ghan 7.5 mg., Raswanti 7.5 mg. & Abhrak Bhasma 7.5 mg.

Hirabol (Myrrh): It contains gum, resin, myr­rhin and myrrhol, a volatile oil and a bitter principle. It is used traditionally internally for leucorrhoea, sub-involution of uterus, cervicitis, chronic endometritis, irregular menses, as an antiseptic and uterine restorative during and after puerperium and as post partum hygienic toner.

Guggul: It is also an olio-resin with similar properties and used in chronic diseases like leucorrhoea, endometritis, amenorrhoea, backache and girdle pain.

Bang Bhasma: It is used in diseases of Genito-urinary organs. It improves health, strengthens the organs and nourishes whole body. It is useful in Leucorrhoea & Menstrual Disorders.

Kasis (easily assimilable iron): It is haematinic.

Shilajit: It is used in genito-urinary diseases, leucorrhoea, leucorrhoea from debility and is a tonic in anaemia and general debility.

Lodhar: Useful in Leucorrhoea, menorrhagia due to relaxation of uterine tissue. Reduces mucous secretion by imparting strength to muc­ous membrane. It is cooling and mild astrin­gent.

Dhavdi Flower: It is astringent & tonic. Useful in Leucorrhoea and diseases of mucous mem­brane.

Ardusi Leaves & Ardusi Ghan: It is diuretic, anti-spasmodic, alterative.

Raswanti: It is tonic, stomachic, astringent, alterative. Useful in Uterine weakness, burning sensation in vagina, leucorrhoea, painful mic­turition etc.

Abhrak Bhasma: It is a standard alternative to other anti-leucorrhic drugs.

Material and Methods

The present study was conducted on pa­tients who attended as Out-Patients in the De­partment of Obstetrics and Gynaecology of Government General Hospital, Kakinada during the period from January 1993 to Sep­tember 1993. It is a randomized study. 100 women with a complaint of white discharge were taken in the study. The patients were subjected to detailed history, physical examination and in­vestigations. 50 patients were followed for ac­curate results.

Investigations: Routine investigations like Hb. %, Urine for Albumin, Sugar and micros­copic examination were done. The vaginal swab was taken and sent for Microbial examination and culture sensitivity to know the causative organisms.

Dosage adopted: The dose adopted was Myron 2 tds for two weeks followed by 2 bd for two weeks. If no improvement was noted in two weeks, then the dosage regime was Myron 2 tds for two weeks followed by Myron 2 bd for

two weeks. The treatment was continued dur­ing menstruation also. They were asked to come for checkup, every week till they got cured.

Observations & Discussions

1. Age Group: Table 1 shows the age group of 50 patients. 27 patients (54%) belong to 21-30 years age group.

Table No. 1

Age Groups

       

Age Group           No. of cases         Percentage
15-20 years 13 26
21-30 27 54
31-40 6 12
41-45 2 4
46-50 2 4

 

2. Marital status and parity: Majority of patients (40%) are multipara. It was observed gener­ally that the number of cases increased with an increasing parity.

Table No. 2
Marital Status & Parity       

Marital Status         No. of cases         Percentage
Unmarried Nil Nil
Nullipara 4 8
Para I 7 14
Para II 18 40
Multipara 20 2
Sterility 1 2

3. Menstrual History: Menstruation was regular in majority of cases. A few cases had menor­rhagia and increased frequency of menstrua­ Two of them were post-menopausal. Two of them had undergone hysterectomy previ­ously. Two of them had lactational amenor­rhoea.

4. Investigations: Most of the patients were Majority of the patients had non­specific leucorrhoea and few of them had mixed infections alongwith trichomoniasis and can­didiasis.

5. Results: Effects of Myron therapy is given in Table No. 3 

 Table No. 3

                   Effects of Myron Treatment on Leucorrhoea

                           Leucorrhoea       Good           Moderate                 Poor/None
Specific 1(7.1%) 5 (35.5%)  

8 (56.0%)

 
Non-specific 20(55.6%) 8(22.2%)  

8(22.2%)

 
Total 21(42.0%) 13 (26.0%)  

16(32.0%)

 

       

 There was complete relief from leucorrhoea in 21 patients (42,0%). Moderate relief in 13 pa­tients (26%) and no or poor relief in 16 patients (32%). The response was comparatively better in non-specific leucorrhoea.

Summary

Leucorrhoea is found mostly in 21-30 years age group. Most of them were multipara. A course of 4 weeks Myron therapy gave com¬plete relief in about half of the cases and there was moderate response in another one-fourth of the patients. Most of the patients had symptomatic relief. The response is better in non-specific leucorrhoea and also in post¬operative leucorrhoea. No toxic or side effects were observed in the use of Myron tabets.

 Acknowledgements

We are grateful to the Department of Mic-robiology, Rangaraya Medical College, Kakinada, and Clinical Laboratory of Govt. General Hospital, Kakinada for their kind co-op¬eration.  

References

  1. Gupta-Leucorrhoea due to non-specific factors (usefulness of an Ayurvedic drug -Myron). Indian Pract. 20: 10, 1967.
  2. Subhadra Devi, N., Rani Hithavachani C and Vijayalakshmi N – Therapeutic trial with Myron in non-specific leucorrhoea, Medis­cope, 16:3, 1973.
  3. C. Bhargava, U. Saxena, R. S. Nanda and R. Seth – Indian Journal of S.T.D.. 1:45-7, 1980.
  4. Rao M. K. – Leucorrhoea and its treatment with an indigenous drug Myron, Mediscope, 19:121-126, 1976.

for information of ALARSIN products
please write to: ALARSIN Marketing Pvt. Ltd.
Alarsin House, A/32, Road No. 3, M.I.D.C., Andheri (E), Bombay-400 093.